Abbexa Ltd's Mucolipin 1 (MCOLN1) Antibody is a Rabbit Polyclonal antibody. This antibody has been shown to work in applications such as: EIA, Immunoassay, ELISA, Immunohistochemistry, and Western Blot. The Mucolipin 1 (MCOLN1) Antibody was generated using MCOLN1, and mucolipin TRP cation channel 1 as the antigen and it reacts with Homo Sapiens, and Human.
Description
This gene encodes a memberof the transient receptor potential (TRP) cation channel gene family. The transmembrane protein localizes to intracellular vesicular membranes including lysosomes, and functions in the late endocytic pathway and in the regulation of lysosomal exocytosis. The channel is permeable to Ca (2+), Fe (2+), Na (+), K (+), and H (+), and is modulated by changes in Ca (2+) concentration. Mutations in this gene result in mucolipidosis type IV